Always read the label and follow the directions for use
*At low doses, oral vitamin C is well absorbed, however the degree of absorption decreases as the dose increases. Research shows that while approximately 72% of a 200mg dose of vitamin C is absorbed, less than 50% of a 1250mg dose is absorbed, and the rest is excreted in urine. Despite popular use of supplemental doses of 1000mg vitamin C, higher doses may actually result in a decreased degree of absorption compared to five divided doses of 200mg.
1. Vitamin C. In: Gropper SS, Smith JL, Carr TP. Advanced nutrition and human metabolism 7th ed. Australia: Cengage Learning. 2018. p303-312.
2. Padayatty SJ, Levine M. New insights into the physiology and pharmacology of vitamin C. CMAJ. 2001; 164(3):353-355.
3. Li Y, Schellhorn HE. New developments and novel therapeutic perspectives for vitamin C. [Review]. J Nutr. 2007; 137(10):2171-84.